Betain reduktaza
| Betain reduktaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.21.4.4 | ||||||||
| CAS broj | 125752-87-6 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Betain reduktaza (EC 1.21.4.4, acetil-fosfat trimetilamin:tioredoksin disulfid oksidoreduktaza (formira N,N,N-trimetilglicin)) je enzim sa sistematskim imenom acetil-fosfat trimetilamin:tioredoksin disulfid oksidoreduktaza (formira betain).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- acetil fosfat + trimetilamin + tioredoksin disulfid + H2O betain + fosfat + tioredoksin
Reakcija se odvija u smeru redukcije betaina. Enzim iz Eubakterija kiselinaaminophilum sadrži podjedinice A, B i C. Podjedinica B sadrži selenocistein i piruvoilnu grupu, i odgovorna je za vezivanje sarkozina i otpuštanje metilamina.
- ↑ Wagner, M., Sonntag, D., Grimm, R., Pich, A. Eckerskorn, C., Söhling, B. and Andreesen, J.R. (1999). „Substrate-specific selenoprotein B of glycine reductase from Eubacterium acidaminophilum”. Eur. J. Biochem. 260: 38-49. PMID 10091582.
- ↑ Bednarski, B., Andreesen, J.R. and Pich, A. (2001). „In vitro processing of the proproteins GrdE of protein B of glycine reductase and PrdA of D-proline reductase from Clostridium sticklandii: formation of a pyruvoyl group from a cysteine residue”. Eur. J. Biochem. 268: 3538-3544. PMID 11422384.
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